Design and Evaluation of Gemini Surfactant-Based Lipoplexes Modified with Cell-Binding Peptide for Targeted Gene Therapy in Melanoma Model.

Conclusion The gemini surfactant-based lipoplexes modified with p18-4 peptide showed significantly higher efficiency and safety compared to the system that did not contain a cancer targeting peptide and provided evidence for their potential application to achieve targeted melanoma gene therapy. PMID: 30266136 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/30266136?dopt=Abstract

Source: J Pharm Pharm Sci - October 1, 2018 Category: Drugs & Pharmacology Authors: Mohammed-Saeid W, Soudy R, Tikoo R, Kaur K, Verrall RE, Badea I Tags: J Pharm Pharm Sci Source Type: research