Prevalence of Adverse Events in Children with Congenital Hyperinsulinism Treated with Diazoxide.

Conclusions: In this large cohort, PH occurred in infants with underlying risk factors, but no identifiable risk profile emerged for other adverse events. The relatively high prevalence of neutropenia, thrombocytopenia, and hyperuricemia suggests the value in proactively screening for these side effects in children treated with diazoxide.
PMID: 30247666 [PubMed - as supplied by publisher]

Source: The Journal of Clinical Endocrinology and Metabolism - September 21, 2018 Category: Endocrinology Authors: Herrera A, Vajravelu ME, Givler S, Mitteer L, Avitabile CM, Lord K, De León DD Tags: J Clin Endocrinol Metab Source Type: research