Mediastinal Myeloid Sarcoma with TP53 Mutation Preceding Acute Myeloid Leukemia with a PICALM-MLLT10 Fusion Gene.
CONCLUSION: MS with a mediastinal localization is rare and often misdiagnosed as malignant lymphoma. Acute leukemia harboring a PICALM-MLLT10 fusion gene is characterized by a mixed T cell and myeloid phenotype. The rearrangement is a rare recurrent translocation associated with specific clinical features, as illustrated in this case report.
PMID: 30227397 [PubMed - as supplied by publisher]
Source: Acta Haematologica - Category: Hematology Authors: Naesens L, Devos H, Nollet F, Michaux L, Selleslag D Tags: Acta Haematol Source Type: research
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