Establishment, functional and genetic characterization of a colon derived large cell neuroendocrine carcinoma cell line.

CONCLUSION: We successfully established and characterized a novel patient-derived NEC cell line in parallel to a PDX model as a useful tool for further analysis of the biological characteristics and for development of novel diagnostic and therapeutic options for NEC.
PMID: 30197480 [PubMed - in process]

Source: World Journal of Gastroenterology : WJG - September 7, 2018 Category: Gastroenterology Authors: Gock M, Mullins CS, Harnack C, Prall F, Ramer R, Göder A, Krämer OH, Klar E, Linnebacher M Tags: World J Gastroenterol Source Type: research