Anti-Vascular endothelial growth factor therapy impairs endothelial function of retinal microcirculation in colon cancer patients – an observational study

Conclusions Bevacizumab acutely impairs microvascular function independent of blood pressure changes. Imaging of the retinal microcirculation seems a valuable tool for monitoring pharmacodynamic effects of bevacizumab. Trial registration NCT ID: NCT00740168
Source: Experimental and Translational Stroke Medicine - Category: Neurology Source Type: research