The interplay between cell death signaling pathways in the heart

To date, one of the most intriguing and compelling concepts to impact contemporary cell biology is the notion that cell fate is “programmed” or genetically controlled. Indeed, the regulation of cell fate is crucial for embryonic development, and tissue homeostasis. Given the importance of removing damaged or irreversibly injured cells from the body, it is not surprising that defects in the regulatory mechanisms that govern cell death and/or survival more generally have been implicated in a number of human pathologies including cancer, neurodegenerative diseases, and cardiac failure.
Source: Trends in Cardiovascular Medicine - Category: Cardiology Authors: Source Type: research