Resistant/susceptible classification of respiratory tract pathogenic bacteria based on volatile organic compounds profiling.

This study demonstrated that resistant strains of bacteria produced VOCs that were different from those of the standard strains. In addition, VOCs released by bacteria after passing the logarithmic growth phase showed no significant differences. The identification of VOCs can be a precise way to differentiate bacterial species, also it can be said that the VOCs produced by different pathogenic microorganisms can be the suitable biomarkers for their detection. PMID: 30030949 [PubMed - in process]
Source: Cellular and Molecular Biology - Category: Molecular Biology Tags: Cell Mol Biol (Noisy-le-grand) Source Type: research

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The antimicrobial inhibitory effects of five common antiseptics [Chlorhexidine (CHX), Hydrogen peroxide (H2O2), Iodine, Ethanol and Dettol] were investigated using agar well diffusion method. The organisms used included methicillin-resistant Staphylococcus aureus (MRSA), Acinetobacter baumannii, Escherichia coli, Klebsiella species and Pseudomonas aeruginosa. The undiluted concentrations of ...
Source: African Journal of Microbiology Research - Category: Microbiology Source Type: research
ConclusionThe GC-MS analysis revealed that five active compounds were present in the extract of this plant. Data obtained, suggested that the C. copticum extracts applied as antimicrobial agents against these pathogens particularly in biofilm making.
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research
Abstract The spreading of antibiotic-resistant pathogens boosted the search for new antimicrobial drugs. Proline-rich antimicrobial peptides are promising lead compounds for the development of next-generation antibiotics, due to their very low cytotoxicity and their good antimicrobial activity targeting the bacterial ribosome. Bac5(1-25) is a N-terminal fragment of the bovine proline-rich antimicrobial peptide Bac5 whose mode of action has been recently described. In this work we tested a number of Bac5(1-25) fragments and we characterized their antimicrobial activity against Escherichia coli, Acinetobacter bauman...
Source: ChemMedChem - Category: Chemistry Authors: Tags: ChemMedChem Source Type: research
Publication date: 1 April 2019Source: Sensors and Actuators B: Chemical, Volume 284Author(s): Chih-Hung Wang, Jiunn-Jong Wu, Gwo-Bin LeeAbstractA bacterial “systematic evolution of ligands by exponential enrichment” protocol was developed herein to identify nucleic acid aptamers capable of binding molecules from three common nosocomial and antibiotic-resistant bacteria: Acinetobacter baumannii, Escherichia coli, and multidrug-resistant Staphylococcus aureus. This high-affinity and high-specificity process featured three selection stages for screening of bacteria-specific aptamers, and the aptamers identified we...
Source: Sensors and Actuators B: Chemical - Category: Chemistry Source Type: research
In conclusion, it was suggested that L. tigrinus can be used as a natural source due to its antioxidant and antimicrobial activities. PMID: 30515206 [PubMed]
Source: Advances in Pharmacological Sciences - Category: Drugs & Pharmacology Tags: Adv Pharmacol Sci Source Type: research
ConclusionThis study shows low resistance to meropenem and tigecycline among the Enterobacteriaceae, and continued activity of linezolid, vancomycin and tigecycline against Gram-positive organisms. However, antimicrobial resistance continues to be problematic in Eastern Europe and requires continued surveillance.
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Conclusion: Evaluation of in-vitro activity clearly indicated TTO as a potential effective antimicrobial treatment either alone or in association with known drugs against MDR. Therefore, TTO could represent the basis for a possible role in non-conventional regimens against S. aureus and Gram-negative MDR. TTO in VP might represent a promising option for local therapy of pneumonia caused by CR-Ab.
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
AbstractBackgroundTreatment and prevention of wound infection continues to be a challenging issue in clinical settings of Nepal especially in the context of globally growing problem of antimicrobial resistance. Study on opportunistic pathogens and sensitivity to commonly prescribed local antimicrobial agents are cardinal to reduce the disease burden of wound infections. The aim of this study was to determine the prevalence and antimicrobial susceptibility pattern of methicillin resistantStaphylococcus aureus (MRSA) and extended spectrum β-lactamase (ESBL) producing bacteria from wound infections of patients at a terti...
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research
ConclusionsHigh bacterial contamination of frequently touched objects with variety of potential pathogens and normal flora was detected.S. aureus was the most common bacterial isolate. Biofilm forming ability offers additional survival advantage to the organisms on these objects. Present study highlights the need of improved hand hygiene among healthcare workers and regular cleaning/disinfection of sites of frequent public contact.
Source: Antimicrobial Resistance and Infection Control - Category: Infectious Diseases Source Type: research
Burn infections pose a serious obstacle to recovery. To investigate and analyze the antimicrobial resistance and distribution of pathogenic bacteria among hospitalized burn patients. A 3-year retrospective study was conducted in the southeast of China. The electronic medical records system was used to collect all clinical data on 1449 hospitalized patients from Fujian Medical University Union Hospital, the 180th Hospital of Chinese People's Liberation Army (PLA), the 92nd Hospital of PLA, and the First Hospital of Longyan City. A total of 1891 strains of pathogenic bacteria were detected from 3835 clinical specimens, and...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
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