Small dense LDL cholesterol in human subjects with different chronic inflammatory diseases

Publication date: Available online 4 July 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): D.M. Schulte, K. Paulsen, K. Türk, B. Brandt, S. Freitag-Wolf, I. Hagen, R. Zeuner, J.O. Schröder, W. Lieb, A. Franke, S. Nikolaus, U. Mrowietz, S. Gerdes, S. Schreiber, M. LaudesAbstractBackground and AimsChronic inflammatory diseases (CID) are associated with a profound increase in cardiovascular (CV) risk resulting in reduced life expectancy. However, LDL-cholesterol is reported to be low in CID patients which is referred to as the “LDL paradoxon”. The aim of the present study was to investigate whether LDL-particles in CID exhibit an increased content of the highly atherogenic small-dense LDL subfraction (sdLDL).Methods and ResultsIn this prospective, single center, observational study we enrolled 141 patients with CID (RA n=59, inflammatory bowel disease (IBD) n=35, ankylosing spondylitis (SpA) n=25, Psoriasis n=22) in 2011 through 2013 to evaluate sdLDL levels before as well as 6 and 26 weeks after initiation of different anti-cytokine therapies (anti-TNFα, anti-IL-6R antibodies). sdLDL levels were compared to 141 healthy individuals in a case control design. Compared to healthy controls, all CID patients displayed a significantly higher sdLDL content within the LDL cholesterol fraction: RA 35.0±9.2% (p
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research

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Authors: Nisker J Abstract Dissolution of Canada's single-tiered health system is now before the Supreme Court of British Columbia and will soon be before the Supreme Court of Canada. If our Supreme Court justices are persuaded to dissolve the Canada Health Act, financially advantaged Canadians will be permitted to purchase privileged access to physicians, diagnostic tests, and surgical facilities. This queue jumping will diminish access for the socioeconomically disadvantaged, among whom women are overrepresented, including women living with disabilities, women of Indigenous heritage, and women who have recently i...
Source: Journal of Obstetrics and Gynaecology Canada : JOGC - Category: OBGYN Tags: J Obstet Gynaecol Can Source Type: research
Conclusion Despite understanding the need for HH during pregnancy, women still need encouragement to practice PE during pregnancy, as well as more information about GWG.Resumo Objetivo O objetivo deste estudo foi investigar os conhecimentos sobre ganho de peso gestacional (GPG), nutri ção, e exercício físico (EF) em gestantes e o quanto elas os colocam em prática. Métodos Estudo transversal realizado no Hospital da Mulher, CAISM, Unicamp, com 61 gestantes acima das 26 semanas gestacionais. Questionários sobre conhecimento de hábitos saudáveis (HS) durante a ges...
Source: Revista Brasileira de Ginecologia e Obstetricia - Category: OBGYN Source Type: research
Source: Critical Reviews in Food Science and Nutrition - Category: Nutrition Authors: Source Type: research
Source: Critical Reviews in Food Science and Nutrition - Category: Nutrition Authors: Source Type: research
Source: Critical Reviews in Food Science and Nutrition - Category: Nutrition Authors: Source Type: research
Source: Critical Reviews in Food Science and Nutrition - Category: Nutrition Authors: Source Type: research
Source: Critical Reviews in Food Science and Nutrition - Category: Nutrition Authors: Source Type: research
Source: Critical Reviews in Food Science and Nutrition - Category: Nutrition Authors: Source Type: research
Publication date: Available online 4 July 2018Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): D.M. Schulte, K. Paulsen, K. Türk, B. Brandt, S. Freitag-Wolf, I. Hagen, R. Zeuner, J.O. Schröder, W. Lieb, A. Franke, S. Nikolaus, U. Mrowietz, S. Gerdes, S. Schreiber, M. LaudesAbstractBackground and AimsChronic inflammatory diseases (CID) are associated with a profound increase in cardiovascular (CV) risk resulting in reduced life expectancy. However, LDL-cholesterol is reported to be low in CID patients which is referred to as the “LDL paradoxon”. The aim of the present study was to in...
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
Publication date: Available online 19 May 2018 Source:Joint Bone Spine Author(s): Clément Prati, Céline Demougeot, Xavier Guillot, Maxime Sondag, Frank Verhoeven, Daniel Wendling Ankylosing spondylitis (AS) is a chronic inflammatory joint disease that involves the entheses, causing inflammatory pain and functional impairments. Patients may experience extraarticular manifestations such as uveitis, psoriasis, and inflammatory bowel disease. These, together with the increased risk of cardiovascular disease and osteoporosis and the development of spinal fusion, are the main determinants of adverse disease outcom...
Source: Joint Bone Spine - Category: Orthopaedics Source Type: research
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