The Tumor Mutational Burden of Chinese Advanced Cancer Patients Estimated by a 381-cancer-gene Panel

Conclusion: The 381-cancer gene panel is a clinical practicable method to assess tumor mutational burden compared with whole exome sequencing. MMR and DDR deficiency are correlated with higher tumor mutational burden of Chinese patients with advanced solid tumors.

Source: Journal of Cancer - June 20, 2018 Category: Cancer & Oncology Authors: Wu Zhuang, Junxun Ma, Xudong Chen, Guoqiang Wang, Jing Lu, Yanan Chen, Hua Dong, Shangli Cai, Yuzi Zhang, Xiaochen Zhao, Youcai Zhu, Chunwei Xu, Yunjian Huang, Zhangzhou Huang, Xiaofeng Zhu, Hong Jiang, Zhijie Wang Tags: Research Paper Source Type: research