Volumetric bone mineral density of the spine predicts mortality in African-American men with type 2 diabetes

ConclusionsLower vBMD was associated with increased all-cause mortality in African-American men with T2D, independent of other risk factors for mortality including subclinical atherosclerosis.
Source: Osteoporosis International - Category: Orthopaedics Source Type: research

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This study investigated the relationship of American Indian boarding school attendance and chronic physical health. We hypothesized boarding school attendance would be associated with an increased number of chronic physical health problems. We also examined the relationship between boarding school attendance and the 15 chronic health problems that formed the count of the chronic health conditions. American Indian attendees had a greater count of chronic physical health problems compared with nonattendees. Father's attendance was independently associated with chronic physical health problems. Attendees were more likely to h...
Source: Family and Community Health - Category: Primary Care Tags: Health Equity Source Type: research
The objective of this study was to evaluate screw choices for three-dimensional (3D) digital pre-operative planning of osteosynthesis of distal radius fractures and to compare with the screw choices for the conventional method. METHODS: Distal radius fracture patients who underwent osteosynthesis using volar locking plates were evaluated. Thirty wrists in the plan group utilized 3D preoperative planning, and nineteen wrists in the control group utilized conventional preoperative assessment. In the plan group, the 3D preoperative planning was performed prior to surgery. The reduction was simulated with 3D image, and th...
Source: Hand Surgery - Category: Surgery Authors: Tags: J Hand Surg Asian Pac Vol Source Type: research
CONCLUSIONS: We believe that computer-assisted 3D corrective osteotomy using prefabricated bone graft substitute achieved good results because it worked as a guide to the accurate angle. PMID: 30428808 [PubMed - in process]
Source: Hand Surgery - Category: Surgery Authors: Tags: J Hand Surg Asian Pac Vol Source Type: research
This study aims to evaluate the accuracy of patient-specific computed tomography (CT)-based rapid prototype drill guide templates for the CBT technique. CT scanning was performed in 7 cadaveric thoracolumbar spines, and a 3-dimensional reconstruction model was generated. By using computer software, we constructed drill templates that fit onto the posterior surface of thoracolumbar vertebrae with drill guides to match the CBT. In total, 80 guide templates from T11 to L5 were created from the computer models by using rapid prototyping. The drill templates were used to guide the drilling of CBT screws without any fluoroscopic...
Source: Techniques in Orthopaedics - Category: Orthopaedics Tags: Novel Research Methods and Models Source Type: research
Purpose: To compare foveal vascular anatomy between patients with and without disorganization of retinal inner layers (DRILs) after resolved diabetic macular edema using optical coherence tomography angiography (OCTA). Methods: Twenty-four eyes of 21 age- and sex-matched patients with resolved diabetic macular edema were included in this retrospective, cross-sectional study. All eyes were imaged with enhanced high-definition line or cross-line structural B scans and 3 × 3-mm OCTA scans. Optical coherence tomography B scans were analyzed for the presence of DRIL, and based on this, eyes were classified as either ...
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
Conclusion: There are significant differences between patients with AMD and DME regarding compliance and adherence, which also affects outcome. Strategies to tie patients with DME to costly intravitreal therapy need to be developed to improve outcomes and efficacy.
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
Purpose: Retinal neovascularizations in proliferative diabetic retinopathy have been proposed to develop from larger retinal venules. However, angiographic evidence suggests that the new vessels may originate from both arterioles and venules, and the vitreous oxygen tension near retinal neovascularizations is similar to that of retinal arterioles. An assessment of the oxygen saturation in neovascularizations may help characterizing the vascular origin of these vessels in proliferative diabetic retinopathy. Methods: Dual wavelength oximetry was used to study the oxygen saturation in arterioles, venules, and retinal neo...
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
Purpose: To determine the association between the dexamethasone implant position in the vitreous cavity and ocular hypertension (OHT). Methods: Retrospective review of patients with at least one intravitreal dexamethasone implant injection between 2012 and 2016. Patients who had a minimum follow-up for 6 months and documented evidence of the implant position were included in the study. Steroid responders, glaucoma patients, vitrectomized eyes, and eyes with liquefied vitreous were excluded. Relevant data were collected from patient charts. Three positions (P1, P2, and P3) were identified: P1 (in contact with the pars ...
Source: RETINA - Category: Opthalmology Tags: Original Study Source Type: research
In this study, the therapeutic effects of buckwheat hull flavonoids (BHFs) on type 2 diabetes db/db mice were investigated. After administration by BHFs nine weeks, body weight, visceral index, biochemical indicators in serum and in liver were detected. The liver pathological changes were observed under microscopic observations. Real-time quantitative PCR was used to detect IRS-1, PI3kα, AKT2, SREBP-1c, FAS, ACC1 mRNA expression in liver. The results showed that insulin resistance significantly reduced after the BHFs treatment. BHFs could reduce the TG, TC, vLDL-c, FFA levels in serum and TG, TC levels in liver and p...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
This study was aimed at evaluating how alloxan-induced diabetes alters the relaxation of the isolated rat renal artery (RA) to resveratrol and determining whether prolong hyperglycemia modifies the expression of potassium (K) channels in the wall of RA. Diabetes reduced the sensitivity to resveratrol in RA. According to K channel blocker affinity, it seems that different subtype of K channels were involved in the resveratrol-induced relaxation of RA of normal rats and only voltage-sensitive Kv1 channels took part in the resveratrol effect on the RA of diabetic rats. Endothelial dysfunction developed during diabetes led to ...
Source: Journal of Functional Foods - Category: Nutrition Source Type: research
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