AEG-1 Contributes to Metastasis in Hypoxia-Related Ovarian Cancer by Modulating the HIF-1alpha/NF-kappaB/VEGF Pathway.

Conclusions: As an independent prognostic factor, AEG-1 was found to be significantly associated with hypoxia in ovarian cancer by regulating the HIF-1alpha/NF-kappaB/VEGF pathway. Therefore, AEG-1 may be useful in determining disease stage and prognosis in ovarian cancer.
PMID: 29770329 [PubMed - in process]

Source: Biomed Res - May 18, 2018 Category: Research Authors: Yu X, Wang Y, Qiu H, Song H, Feng D, Jiang Y, Deng S, Meng H, Geng J Tags: Biomed Res Int Source Type: research