Nanoparticle based treatment for Cardiovascular Diseases.

Nanoparticle based treatment for Cardiovascular Diseases. Cardiovasc Hematol Disord Drug Targets. 2018 May 07;: Authors: Jayant RD, Gupta P, Garcia E, Sarkar A, Kapoor S, Rafiq K, Chand HS, Nair M Abstract Nanotechnology has gained increased attention for delivering therapeutic agents effectively to the cardiovascular system. Heart targeted nanocarrier based drug delivery is a new, effective and efficacious approach for treating various cardiac related disorders such as atherosclerosis, hypertension, and myocardial infarction . Nanocarrier based drug delivery system circumvents the problems associated with conventional drug delivery systems, including their non-specificity, severe side effects and damage to the normal cells. Modification of physicochemical properties of nanocarriers such as size, shape and surface modifications can immensely alter its in-vivo pharmacokinetic and pharmacodynamic data and will provide better treatment strategy. Several nanocarriers such as lipid, phospholipid nanoparticles have been developed for delivering drugs to the target sites within the heart. This review summarizes and increases the understanding of the advanced nanosized drug delivery systems for treating cardiovascular disorders with the promising use of nanotechnology. PMID: 29737265 [PubMed - as supplied by publisher]
Source: Cardiovascular and Hematological Disorders Drug Targets - Category: Drugs & Pharmacology Tags: Cardiovasc Hematol Disord Drug Targets Source Type: research

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