Infant Formula Feeding Increases Hepatic Cholesterol 7 α Hydroxylase (CYP7A1) Expression and Fecal Bile Acid Loss in Neonatal Piglets

ConclusionsThese results indicate that formula feeding leads to increased CYP7A1 protein expression and fecal bile acid loss in neonatal piglets, and this outcome is linked to reduced efficacy in inhibiting CYP7A1 expression through FGF19 and SHP transcriptional repression mechanisms.
Source: Journal of Nutrition - Category: Nutrition Source Type: research