Enteritis as initial manifestation of systemic lupus erythematosus in early pregnancy: A case report

We report of a patient who presented with enteritis as manifestation of new-onset SLE during the first trimester of pregnancy. Patients concerns: The 23-year nulliparous patient was admitted to a district hospital with abdominal pain, nausea, vomiting and bloody diarrhea at a gestational age (GA) of 10 weeks. Her symptoms improved with symptomatic treatment and she was discharged a few days later. At 15 weeks’ of gestation she was readmitted. Her lab results revealed mild anemia and thrombocytopenia. Ascites, renal failure and proteinuria developed. An infectious cause was suspected, but stool samples and urine cultures were negative. Diagnostic work-up included abdominal ultrasound, gastro- and sigmoidoscopy, magnetic resonance imaging (MRI), and diagnostic laparoscopy. Ultrasound and MRI revealed dilated, fluid-filled small bowel loops, and increased colonic wall diameters. Mucosal edema and petechiae were detected by sigmoidoscopy, and histopathologic examination of the biopsies revealed erosive inflammation. Due to progressive deterioration she was transferred to our center. In addition to ascites, pleural and pericardial effusions had developed. Diagnosis: Diagnosis of SLE was finally established at GA 16 after an autoimmune workup revealed positive antinuclear, anti- Sm, anti-dsDNA and anti-U1RNP antibodies. An interdisciplinary team was set up for her management. She was commenced on corticosteroids; response was only partial and necessitated addition of cy...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

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Authors: Xu M, Luo L, Du M, Tang L, Hu Y, Mei H Abstract Bleeding is the most common clinical symptom and the leading cause of death in patients with primary immune thrombocytopenia (ITP). Our research intends to verify the role of fibrinogen levels as independent determinants of bleeding. We retrospectively analyzed the relationship between fibrinogen levels and bleeding events in 463 patients. Additionally, we confirmed the impact of fibrinogen level on clot firmness in 25 patients via thrombelastography (TEG). Fibrinogen levels (median and inter-quartile range, IQR) were significantly different (p
Source: Platelets - Category: Hematology Tags: Platelets Source Type: research
CONCLUSIONS: This survey provided a comprehensive update of the present cataract surgery practices in the Republic of Korea. The results emphasized the increasing use of premium intraocular lenses, optical biometry, and topical anesthesia. PMID: 31612656 [PubMed - in process]
Source: Korean Journal of Ophthalmology : KJO - Category: Opthalmology Tags: Korean J Ophthalmol Source Type: research
University of Rochester Medical Center researchers have been selected as part of a national initiative by the National Institutes of Health to develop new non-addictive treatments for pain to improve patient care and curb the use and abuse of opioids.
Source: University of Rochester Medical Center Press Releases - Category: Universities & Medical Training Authors: Source Type: news
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Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Pain Medicine Source Type: forums
ConclusionRACRS is safe in the treatment of patients with stage I –III colorectal cancer. Oncological outcome did not differ between RACRS and LCRS groups. RACRS had lower conversion and intra-operative complication rates.
Source: Surgical Endoscopy - Category: Surgery Source Type: research
ConclusionsIn conclusion, PLDRH is a feasible and safe procedure with a learning curve of 65 –70 cases.
Source: Surgical Endoscopy - Category: Surgery Source Type: research
This study was performed according to the PRISMA guidelines. A search was performed on Medline, EMBASE, and the Cochrane Library to identify relevant articles. Dichotomous and continuous outcomes were analyzed as risk ratio (RR) and mean difference (MD), respectively. All post-operative outcomes were within 30  days after surgery. The quality of studies was assessed using the Newcastle–Ottawa Scale. Meta-regression analysis was conducted to identify sources of heterogeneity.ResultsThree studies totaling 262 subjects compared LS (45.0%) against RS (55.0%) in obese patients. The RS group had a significantly reduce...
Source: Surgical Endoscopy - Category: Surgery Source Type: research
ConclusionsHSI is suitable for contact-free, non-invasive, and intraoperative evaluation of physiological tissue parameters within gastric conduits. Therefore, HSI is a valuable method for evaluating ischemic conditioning effects and may contribute to reduce anastomotic complications. Additional studies are needed to establish normal values and thresholds of the presented parameters for the gastric conduit anastomotic site.
Source: Surgical Endoscopy - Category: Surgery Source Type: research
AbstractBackgroundHepatectomy remains the only curative option in patients presenting with colorectal liver metastases (CLM). Although laparoscopic approach has improved postoperative morbidity and mortality rates, its suitability for patients of all age groups has yet to be confirmed. The aim of this study was to analyze postoperative outcomes following laparoscopic liver resection (LLR) in different age groups of patients presenting with CLM.MethodsAll patients who underwent LLR for CLM from 2008 to 2017 were reviewed. Patients were divided into four age groups:  75 years. Baseline and intraoperative characte...
Source: Surgical Endoscopy - Category: Surgery Source Type: research
ConclusionEFTR is a safe, minimally invasive treatment modality that ensures complete eradication of the duodenal subepithelial lesions.
Source: Surgical Endoscopy - Category: Surgery Source Type: research
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