A High-fat and High-Cholesterol Diet Potentiates Oxidative Damage in Hippocampus of Mice Lacking Apolipoprotein E.

Conclusion: This highlights the degree to which ApoE deficiency places hippocampal tissue at risk for oxidative damage. Even a modest dietary deficiency may be sufficient to provoke oxidative damage to hippocampal tissue. These results highlight the combinatorial impact of genetic and dietary deficiencies on oxidative damage to hippocampal tissue. PMID: 29541261 [PubMed]

https://www.ncbi.nlm.nih.gov/pubmed/29541261?dopt=Abstract

Source: The Open Neurology Journal - March 18, 2018 Category: Neurology Tags: Open Neurol J Source Type: research