Predominant subcortical accumulation of 18F-flortaucipir binding in behavioral variant frontotemporal dementia

In this study, we sought to investigate 18F-flortaucipir binding patterns and their correlates in clinically-diagnosed bvFTD patients by comparing with results for Alzheimer ’s disease (AD) patients. We enrolled 20 bvFTD, 20 AD and 20 age-matched healthy subjects who underwent neuropsychological tests, magnetic resonance imaging, and tau positron emission tomography scans with 18F-flortaucipir.

Source: Neurobiology of Aging - February 20, 2018 Category: Neuroscience Authors: Hanna Cho, Sang Won Seo, Jae Yong Choi, Hye Sun Lee, Young Hoon Ryu, Myung Sik Lee, Duk L. Na, Hee Jin Kim, Chul Hyoung Lyoo Source Type: research