Neurocognition and Cerebral Lesion Burden in High-Risk Patients Before Undergoing Transcatheter Aortic Valve Replacement: Insights From the SENTINEL Trial

Conclusions
There was a significant proportion of aortic stenosis patients with impaired cognition before TAVR, with a relationship between baseline cognitive function and lesion burden likely attributable to longstanding cerebrovascular disease. These findings underscore the importance of pre-interventional testing and magnetic resonance imaging in any research investigating post-surgical cognitive outcomes in patients with cardiovascular disease.

Source: Journal of the American College of Cardiology: Cardiovascular Interventions - February 19, 2018 Category: Cardiology Authors: Lazar, R. M., Pavol, M. A., Bormann, T., Dwyer, M. G., Kraemer, C., White, R., Zivadinov, R., Wertheimer, J. C., Thöne-Otto, A., Ravdin, L. D., Naugle, R., Mechanic-Hamilton, D., Garmoe, W. S., Stringer, A. Y., Bender, H. A., Kapadia, S. R., Kodal Tags: Structural Source Type: research