Transient Receptor Potential Vanilloid 4 Activation-Induced Increase in Glycine-Activated Current in Mouse Hippocampal Pyramidal Neurons

Conclusion: Activation of TRPV4 increases GlyR function and expression, and PKC and CaMKII signaling pathways are involved in TRPV4 activation-induced increase inIGly. This study indicates that GlyRs may be effective targets for TRPV4-induced modulation of hippocampal inhibitory neurotransmission.Cell Physiol Biochem 2018;45:1084 –1096

https://www.karger.com/Article/FullText/487350

Source: Cellular Physiology and Biochemistry - February 13, 2018 Category: Cytology Source Type: research