Ginger causes subfertility and abortifacient in mice by targeting both estrous cycle and blastocyst implantation without teratogenesis

Conclusions These findings suggest that Ginger can disrupt the oestrous cycle and blastocyst implantation without teratogenesis. Graphical abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research

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This article examined common themes (relating to consent, checking the block, managing intraoperative pain, and professionalism) that emerged from an analysis of these claims and highlighted the lessons to be learned for practicing anesthesiologists.
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Editorials and Reviews Source Type: research
(Am J Obstet Gynecol. 2018;218(1):98–102) The United States Food and Drug Administration has warned against the use of general anesthetics and sedation medications for>3 hours in pregnant women in the third trimester and children younger than 3 years old. The anesthetics agents listed included midazolam, propofol, and inhalational anesthetics (isoflurane, sevoflurane, and desflurane). They claim these agents may affect the development of children’s brains.
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Editorials and Reviews Source Type: research
(Int J Obstet Anesth. 2018;33:53–56) Anesthesiologists face a dilemma when pregnant women with lower back tattoos request epidural analgesia during labor, as clear guidelines have not been established regarding the performance of epidural procedures through a tattoo on the lower back. In the United States ∼25% of people between the ages of 18 and 50 report having a tattoo. The opinions of anesthesiologists vary widely as to how to approach this scenario. In surveys performed addressing the issue, 40% of survey respondents indicated they would not perform an epidural technique through a lumbar tattoo and 70% repo...
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Editorials and Reviews Source Type: research
This study was a systematic review and meta-analysis of randomized controlled trials of prenatal vitamin D supplementation that was undertaken with the goal of estimating the effects of vitamin D supplementation during pregnancy on maternal, neonatal, and infant outcomes.
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Editorials and Reviews Source Type: research
(Acta Obstet Gynecol Scand. 2018;97:235–247) Management for women with gestational diabetes mellitus (GDM) and pregestational diabetes mellitus (DM), includes diet, physical activity, and oral hypoglycemic agents or insulin as needed. However, the optimal schedule, frequency, and timing of glucose monitoring as well as the ideal therapeutic glucose level remain inconclusive. Results from randomized controlled trials (RCTs) have not been able to define any specific criteria for pharmacologic therapy dose adjustment. Therefore, these investigators undertook a systematic review of RCTs in order to analyze the criteria ...
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Editorials and Reviews Source Type: research
This study aimed to investigate whether this dependent coverage provision of the ACA was associated with changes in birth outcomes, utilization of prenatal care, or payment methods for birth.
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Epidemiologic Reports Surveys Source Type: research
(JAMA. 2018;319(12):1239–1247) Between 2004 and 2014, hospital-based obstetric services have decreased from 55% to 46% in rural counties in the United States. Prior studies have shown that women and children in remote rural areas have delayed prenatal care initiation and higher rates of pregnancy hospitalizations, low birth weight, preterm births, and infant mortality. This retrospective cohort study examined whether the loss of rural obstetric services was associated with changes in location of childbirth or outcomes of care.
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Epidemiologic Reports Surveys Source Type: research
(Aust N Z J Obstet Gynaecol. 2018;58:91–97) Pregnancy at advanced maternal age (defined as 35 y or greater at the time of birth) is becoming more common due to advanced fertility and contraceptive techniques and changing sociocultural trends. Pregnancy complications have been reported to occur at a higher rate in these women, including fetal chromosomal abnormalities, gestational diabetes, and hypertensive disorders of pregnancy. It is established that chromosomal abnormalities are directly related to maternal age. The other complications, however, have also generally been attributed to advanced maternal age ...
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Epidemiologic Reports Surveys Source Type: research
This study aimed to investigate induced labor, cesarean delivery, and health care utilization in patients with a previous stillbirth and assess if anxiety and dread of childbirth may be possible causes of the increased cesarean rate and increased frequency of antenatal visits.
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Epidemiologic Reports Surveys Source Type: research
(BMJ. 2018;360:k817) Overuse of cesarean sections throughout the world is a cause of concern due to the potential adverse health effects on the mother and the child. In China, between 2008 and 2014, the cesarean section rate increased from 29% to 35%, although wide variations among provinces existed. To address this issue, the Chinese government introduced various policies and programs at central, provincial, district, county, and hospital levels in an attempt to decrease the rate. As a result, cesarean section rates started to decline, particularly in large urban areas, for example, from 60% in 2009 to 43% in 2014 in Bei...
Source: Obstetric Anesthesia Digest - Category: Anesthesiology Tags: Epidemiologic Reports Surveys Source Type: research
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