New study shows severe toxicity with high-dose AAV9-based gene therapy in animal models

(Mary Ann Liebert, Inc./Genetic Engineering News) Researchers have described severe, life-threatening toxicity in monkeys and piglets given high doses of gene therapy delivered using an adeno-associated virus (AAV9) vector capable of accessing spinal cord neurons.

Source: EurekAlert! - Medicine and Health - January 30, 2018 Category: International Medicine & Public Health Source Type: news