Incidental neuroblastoma with bilateral retinoblastoma: what are the chances?
Incidental neuroblastoma with bilateral retinoblastoma: what are the chances?
Ophthalmic Genet. 2018 Jan 16;:1-4
Authors: Roelofs K, Shaikh F, Astle W, Gallie BL, Soliman SE
Abstract
A child with bilateral familial retinoblastoma underwent staging MRI brain and orbit which identified subtle leptomeningeal enhancement, thus prompting an MRI whole body, which revealed a retroperitoneal mass, confirmed on laparoscopic biopsy to be neuroblastoma. This is the first reported case of these two rare embryonal non-central nervous system tumors occurring concurrently. The cause of this concurrence is unknown despite their pathogenic similarities with a chance of 4 cases per 10 billion children aged 1-4 years. Incidental neuroblastomas in infants can regress spontaneously but this child underwent systemic chemotherapy for his retinoblastoma that may have caused regression of the neuroblastoma.
PMID: 29336617 [PubMed - as supplied by publisher]
Source: Ophthalmic Genetics - Category: Opthalmology Tags: Ophthalmic Genet Source Type: research
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