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Risk reduction surgery (RRS) for tubo-ovarian cancer in an Irish gynaecological practice: an analysis of indications and outcomes

ConclusionMore than 60% of women undergoing RRS were BRCAm negative or untested. Counselling of high-risk women without defined germline mutations remains a challenge for gynaecologists because the likelihood of removing STIC lesions or occult invasive cancer is low. Removal of coincidental pathology may give added value to RRS in these women.
Source: Irish Journal of Medical Science - Category: General Medicine Source Type: research

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Conclusions: The hierarchical structure of the CART model provides a diagnostic algorithm linked with the risk of malignancy at every step of the procedure. It also provides guidance on the use of ancillary examinations as it goes by simple, human understandable rules.Acta Cytologica
Source: Acta Cytologica - Category: Cytology Source Type: research
CONCLUSION: Confirmation of diabetes was abysmally low in the study population. Low uptake of the confirmatory test might be due to low 'risk perception'. The uptake can be increased by improving the population risk perception through individual and/or community-focused risk communication interventions. PMID: 29334333 [PubMed - in process]
Source: Global Health Action - Category: International Medicine & Public Health Tags: Glob Health Action Source Type: research
Authors: Lee SY, Song WH, Oh SC, Min BW, Lee SI Abstract Purpose: Because data as a basis for the determination of proper age and modality for screening of colorectal neoplasms is lacking, we evaluated detection rates and anatomical distribution of colorectal neoplasms according to age in healthy individuals who underwent total colonoscopy for health checkup. Methods: A total of 16,100 cases that had received the colonoscopic examination from January to December in 2014 were analyzed. The total number of individuals who received total colonoscopy were divided by the number of individuals harboring colorectal ad...
Source: Annals of Surgical Treatment and Research - Category: Surgery Tags: Ann Surg Treat Res Source Type: research
Conclusion: In our experience, NOSE for mid- and upper rectal cancer had acceptable long-term oncologic outcomes comparable to those of conventional minimal invasive surgery and seems to be a safe alternative to reduce access trauma. PMID: 29333423 [PubMed]
Source: Annals of Surgical Treatment and Research - Category: Surgery Tags: Ann Surg Treat Res Source Type: research
Conclusion: Hypermethylation of RUNX3 may be a predictor of a poor prognosis in CRC. PMID: 29333422 [PubMed]
Source: Annals of Surgical Treatment and Research - Category: Surgery Tags: Ann Surg Treat Res Source Type: research
Conclusion: In patients with BM from CRC, surgical resection plus SRS might improve survival. PMID: 29333421 [PubMed]
Source: Annals of Surgical Treatment and Research - Category: Surgery Tags: Ann Surg Treat Res Source Type: research
Germany's drug assessment body has criticised a lack of data directly comparing drugs in a promising new class of cancer immunotherapy, saying physicians could be overwhelmed or misled by the available information.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Medscape Today News Source Type: news
STOMACH cancer is considered a fairly uncommon type of cancer but symptoms can be vague and easily mistaken for other less serious conditions. Pain in your stomach, persistent indigestion and feeling sick are just a few of the symptoms. Here are all nine early signs to look out for.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
Org. Biomol. Chem., 2018, Accepted Manuscript DOI: 10.1039/C7OB02957H, PaperMiffy Cheng, Antoine Maruani, Huguette Savoie, Vijay Chudasama, Ross W Boyle We herein report the synthesis and analysis of a novel aza-BODIPY-antibody conjugate, formed by controlled and regioselective bioconjugation methodology. Employing the clinically relevant antibody, which targets HER2 positive cancers, represents... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Organic and Biomolecular Chemistry - Category: Molecular Biology Authors: Source Type: research
AbstractA simplified and cost-effective optical absorber is designed by means of optimization on the basis of finite domain and time difference (FDTD) algorithm. It is suitable for fabrication and mass production in future industry. To investigate its absorbing performance and photo-thermal effect, experiments are carried out using focused ion beam nanofabrication, characterization of spectroscopy, and measurement of temperature rise. Our experimental results demonstrate that the absorber is possible to be used in photo-thermal therapy for tumor/cancer cells.
Source: Plasmonics - Category: Biomedical Science Source Type: research
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