Risk Management for Opioid Prescribing in the Treatment of Patients With Pain From Cancer or Terminal Illness: Inadvertent Oversight or Taboo?

Risk Management for Opioid Prescribing in the Treatment of Patients With Pain From Cancer or Terminal Illness: Inadvertent Oversight or Taboo? Anesth Analg. 2017 Nov;125(5):1610-1615 Authors: Copenhaver DJ, Karvelas NB, Fishman SM Abstract As the United States experiences an epidemic of prescription drug abuse, and guidelines on safe practices in prescribing opioids in chronic pain have subsequently emerged from professional organizations and governmental agencies, limited guidance exists for prescribers of opioids to treat pain in patients with cancer or terminal illness. Patients with active cancer or terminal illness often have pain and are frequently prescribed opioids and other controlled substances. Current studies suggest that patients with cancer have similar rates of risk for misuse, abuse, and addiction as the general public. Moreover, palliative care and hospice programs appear poorly prepared for assessing or managing patients with aberrant behaviors or evidence of drug abuse. Further research and professional consensus are needed to help address the challenges associated with misuse, abuse, and addiction in patients with cancer and terminal illness. PMID: 29049111 [PubMed - in process]
Source: Anesthesia and Analgesia - Category: Anesthesiology Authors: Tags: Anesth Analg Source Type: research

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Cliffside Malibu does not condone the use of the term “addict” when referring to people suffering from the disorder of addiction. However, we do understand that others still may use the term in order to find information. Many people may find themselves asking the question, “am I an opioid addict?” if they feel as if their use has spiraled out of control. There are many ways to find out if you may have become addicted to opioids, as well as ways to get help and find treatment. How Opioid Addiction Begins Nearly 80% of heroin users started with prescription opioids, which puts prescription drugs and ...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction Addiction to Pharmaceuticals addiction treatment opioid opioid crisis opioids pharmaceutical addiction pharmaceutical drug abuse treatment Source Type: blogs
By CLAIRE GALOFARO Associated Press The World Health Organization notified U.S. lawmakers last Wednesday that it will discontinue two publications on prescribing opioid painkillers in response to allegations that the pharmaceutical industry influenced the reports. The pledge to remove the guidelines comes a month after U.S. Reps. Katherine Clark and Hal Rogers accused the WHO of being influenced by Purdue Pharma, the American manufacturer of the potent painkiller OxyContin. The lawmakers' report claimed the guidelines, crafted in part by organizations with financial ties to the company, downplay the risk of opioids despite...
Source: JEMS: Journal of Emergency Medical Services News - Category: Emergency Medicine Authors: Tags: News Patient Care AP News Tag Source Type: news
CONCLUSION: The epidemic of opioid misuse has shown that there is a lack of fundamental knowledge about the characteristics and management of chronic pain, that conflicts of interest and validity of models must be more intensively considered in the context of drug development and that novel analgesics with less addictive potential are urgently needed. Currently, the most promising perspectives appear to be augmenting endogenous opioid actions and the selective activation of peripheral opioid receptors. PMID: 31222410 [PubMed - as supplied by publisher]
Source: Schmerz - Category: Anesthesiology Authors: Tags: Schmerz Source Type: research
 Former Congressman Patrick Kennedy joins our hosts to talk about mental health and addiction parity, both at the federal and state levels. He shares information about new initiatives, dontdenyme.org and parityregistry.org, designed to help consumers file appeals on their own, if they feel they’ve been wrongly denied coverage by their insurance companies. They speak candidly about the problems faced with regard to parity by those who live with mental health or addiction issues. And finally, they talk about how anyone can become an advocate. Subscribe to Our Show! And Remember to Review Us! About O...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Interview Policy and Advocacy The Psych Central Show Gabe Howard Parity Patrick Kennedy Vincent M. Wales Source Type: blogs
With all the news media accounts and reports from governmental health organizations about the opioid epidemic, including the 70,237 drug overdose deaths in 2017, a newly emerging threat is gaining attention: use and misuse of benzodiazepines, opioid drugs and Z-drugs. Specifically, combining these three drugs can create a deadly combination that snuffs out lives. Benzodiazepine Overdose Deaths on the Rise Benzodiazepines, a class of sedative narcotic drugs including Xanax and Valium used to treat anxiety, insomnia and other disorders and classified as Schedule IV under the Controlled Substances Act by the Drug Enforcement ...
Source: Psych Central - Category: Psychiatry Authors: Tags: Addictions Substance Abuse Suicide Source Type: news
CONCLUSION: The epidemic of opioid misuse has shown that there is a lack of fundamental knowledge about the characteristics and management of chronic pain, that conflicts of interest and validity of models must be more intensively considered in the context of drug development and that novel analgesics with less addictive potential are urgently needed. Currently, the most promising perspectives appear to be augmenting endogenous opioid actions and the selective activation of peripheral opioid receptors. PMID: 30645691 [PubMed - as supplied by publisher]
Source: Der Anaesthesist - Category: Anesthesiology Authors: Tags: Anaesthesist Source Type: research
CONCLUSIONS: The opioids "plague" that is striking the USA is not registered in Italy during the observation period. The reasons might be due to the innovative and effective law 38/2010 and a health care system able to guarantee appropriate prescriptions for major analgesics. PMID: 30575575 [PubMed - in process]
Source: Annali dell Istituto Superiore di Sanita - Category: General Medicine Tags: Ann Ist Super Sanita Source Type: research
This study was funded by the National Institute of Mental Health; the National Institute on Drug Abuse; a New Investigator Award from the Canadian Institutes of Health Research; an Early Researcher Award from the Ontario Ministry of Research, Innovation and Science; the UCLA Center for HIV Identification, Prevention and Treatment Services; the UCLA Center for AIDS Research; and the UCLA Clinical Translational Science Institute.
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Prescription opioid use has increased significantly over the past 25 years due to a number of factors including efforts to help patients struggling to cope with pain, overprescribing by providers and marketing by pharmaceutical companies. However, opioids provide euphoria as well as analgesia [1]. This euphoria coupled with iatrogenic physical dependence and addictive qualities has contributed to an epidemic of opioid abuse, addiction and overdose [2]. The increased use of opioids for treating non-cancer chronic pain and the increased use of higher-dose and higher bioavailability formulations has added to what the Centers ...
Source: Surgery for Obesity and Related Diseases - Category: Surgery Authors: Source Type: research
This article reviews pharmacological principles and research strategies aiming at novel opioids with reduced side effects. Basic mechanisms underlying pain, opioid analgesia and other opioid actions are outlined. To illustrate the clinical situation and medical needs, plasticity of opioid receptors, intracellular signaling pathways, endogenous and exogenous opioid receptor ligands, central and peripheral sites of analgesic and side effects are discussed. Expert opinion: The epidemic of opioid misuse has taught us that there is a lack of fundamental knowledge about the characteristics and management of chronic pain, that co...
Source: Expert Opinion on Investigational Drugs - Category: Drugs & Pharmacology Tags: Expert Opin Investig Drugs Source Type: research
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