Adolescents and young adults with brain tumors in the context of molecular advances in neuro ‐oncology

Abstract Adolescents and young adults (AYA) comprise a specific group of oncology patients with a distinct biological and epidemiological spectrum of central nervous system neoplasms. It has been well documented that they differ clinically, especially in relation to prognosis and chemotherapy tolerance; however, the underlying reasons for this are unclear. Recent advances in the genomics of both childhood and adult brain tumors have provided new explanations and insights into the previously described age‐dependent heterogeneity. Herein, we summarize the current state of the AYA population in neuro‐oncology, specifically how biological advances can help personalize therapy for this unique group of patients.
Source: Pediatric Blood and Cancer - Category: Cancer & Oncology Authors: Tags: AYA ONCOLOGY: REVIEW Source Type: research