High yield reproducible rat model recapitulating human Barrett's carcinogenesis.

CONCLUSION: Esophagojejunostomy was successfully replicated in rats with low mortality and a high tumor burden, which may facilitate broader adoption to study EAC development, progression, and therapeutics.
PMID: 28970723 [PubMed - in process]

Source: World Journal of Gastroenterology : WJG - September 7, 2017 Category: Gastroenterology Authors: Matsui D, Omstead AN, Kosovec JE, Komatsu Y, Lloyd EJ, Raphael H, Kelly RJ, Zaidi AH, Jobe BA Tags: World J Gastroenterol Source Type: research