Low-Density Lipoprotein Docosahexaenoic Acid Nanoparticles Induce Ferroptotic Cell Death in Hepatocellular Carcinoma.

CONCLUSION: LDL-DHA induces cell death in HCC cells through the ferroptosis pathway, this represents a novel molecular mechanism of anticancer activity for LDL-DHA nanoparticles.
PMID: 28893626 [PubMed - as supplied by publisher]

Source: Free Radical Biology and Medicine - September 8, 2017 Category: Biology Authors: Ou W, Mulik RS, Anwar A, McDonald JG, He X, Corbin IR Tags: Free Radic Biol Med Source Type: research