[Reversible alterations in the dentate nuclei and rapid-onset cerebral atrophy due to neurotoxicity caused by lithium].

CONCLUSIONS: Although treatment with lithium can cause a variety of neurological side effects, they are usually reversible. However, they occasionally give rise to permanent and disabling sequelae, as in the case of the patient reported here, with a marked and progressive cerebellar atrophy, accompanied by permanent sequelae in the form of a disabling cerebellar syndrome. The cerebellar neurotoxicity of lithium must be taken into account in the broad differential diagnosis of cerebellar ataxia in adults.
PMID: 28849864 [PubMed - in process]

Source: Revista de Neurologia - August 30, 2017 Category: Neurology Authors: Pardina-Vilella L, Garcia-Gorostiaga I, Azkune-Calle I, Vicente-Olabarria I, Martinez-Arroyo A, Bocos-Portillo J, Gomez-Beldarrain M, Garcia-Monco JC Tags: Rev Neurol Source Type: research