Cardiovascular Disease in Acromegaly.

Cardiovascular Disease in Acromegaly.
Methodist Debakey Cardiovasc J. 2017 Apr-Jun;13(2):64-67
Authors: Sharma MD, Nguyen AV, Brown S, Robbins RJ
Abstract
In patients with acromegaly, chronic excess of growth hormone (GH) and insulin-like growth factor-1 (IGF-1) leads to the development of acromegalic cardiomyopathy. Its main features are biventricular hypertrophy, diastolic dysfunction, and in later stages, systolic dysfunction and congestive heart failure. Surgical and/or pharmacological treatment of acromegaly and control of cardiovascular risk factors help reverse some of these pathophysiologic changes and decrease the high risk of cardiovascular complications.
PMID: 28740584 [PubMed - in process]

Source: Methodist DeBakey Cardiovascular Journal - April 1, 2017 Category: Cardiology Authors: Sharma MD, Nguyen AV, Brown S, Robbins RJ Tags: Methodist Debakey Cardiovasc J Source Type: research