The interaction of auraptene and other oxyprenylated phenylpropanoids with glucose transporter type 4

Conclusions : Among the compounds assayed, auraptene showed to possess potentialities to be a potent activator of both translocation of GLUT4 and glucose influx into skeletal muscle cells with the highest bioavailability among effective compounds. Its capacity to modulate sugar metabolism, coupled to its presence in edible Citrus fruits, can be regarded as an additional reason to account for the already known stimulating properties of some vegetable (e.g. bitter orange). Graphical abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research