Space and location of cerebral microbleeds, cognitive decline, and dementia in the community

Conclusions:
Mixed or a higher load of CMBs, with some specificity for location, is associated with accelerated cognitive decline in older people. These findings suggest a role for hypertensive vasculopathy and the combined effect of hypertensive and cerebral amyloid angiopathy in the pathogenesis of cognitive deterioration.

Source: Neurology - May 29, 2017 Category: Neurology Authors: Ding, J., Sigurthsson, S., Jonsson, P. V., Eiriksdottir, G., Meirelles, O., Kjartansson, O., Lopez, O. L., van Buchem, M. A., Gudnason, V., Launer, L. J. Tags: MRI, Other cerebrovascular disease/ Stroke, Vascular dementia, Cognitive aging, Cohort studies ARTICLE Source Type: research