PM2.5-induced alterations of cell cycle associated gene expression in lung cancer cells and rat lung tissues

In conclusion, PM2.5 can induce significantly alterations of p53 and CDK2 in the early phase, Cdc2 and cyclin B in mid-term and p21 in long-term exposure. The degree of PM2.5-induced damage to the trachea and lung tissue was time-dependent.
Source: Environmental Toxicology and Pharmacology - Category: Environmental Health Source Type: research