Dynamic Changes in Aortic Vascular Stiffness in Patients Bridged to Transplant  With Continuous-Flow Left Ventricular Assist Devices

Conclusions Aortic stiffness is markedly increased immediately post-OHT among patients bridged with CF-LVADs, with attenuation of this increased stiffness over the first year after transplant. These results suggest that aortic vascular properties are dynamic and may be influenced by alterations in flow pulsatility. As more patients are supported with CF-LVADs and as newer pump technology attempts to modulate pulsatility, further research examining the role of alterations in flow patterns on vascular function and the potential resultant systemic sequelae are needed. Graphical abstract
Source: JACC: Heart Failure - Category: Cardiology Source Type: research