High ‐risk epithelial ovarian cancer patients for hereditary ovarian cancer

ConclusionUp to 30% of EOC patients had risk factors for hereditary ovarian cancer. Germline mutation was identified in 28.6% of patients (11.4% BRCA mutation, 5.7% other HR genes mutation, 8.6% MMR mutation, and 2.9% mutation in other gene). The high cost of genetic testing is an important barrier. Selected patients with high‐risk factors might be initially considered for genetic testing in a limited‐resource setting.

Source: Journal of Obstetrics and Gynaecology Research - February 10, 2017 Category: OBGYN Authors: Seksit Chirasophon, Tarinee Manchana, Chinachote Teerapakpinyo Tags: Original Article Source Type: research