Metformin during ovulation induction with gonadotrophins followed by timed intercourse or intrauterine insemination for subfertility associated with polycystic ovary syndrome.

CONCLUSIONS: Preliminary evidence suggests that metformin may increase the live birth rate among women undergoing ovulation induction with gonadotrophins. At this moment, evidence is insufficient to show an effect of metformin on multiple pregnancy rates and adverse events. Additional trials are necessary before we can provide further conclusions that may affect clinical practice.
PMID: 28118681 [PubMed - as supplied by publisher]

Source: Cochrane Database of Systematic Reviews - January 23, 2017 Category: Journals (General) Authors: Bordewijk EM, Nahuis M, Costello MF, Van der Veen F, Tso LO, Mol BW, van Wely M Tags: Cochrane Database Syst Rev Source Type: research