Activation of GR but not PXR by Dexamethasone Attenuated Acetaminophen Hepatotoxicities via Fgf21 Induction.

In conclusion, via GR activation, DEX induced Fgf21 expression in mouse liver and human hepatoma cells.
PMID: 28088388 [PubMed - as supplied by publisher]

Source: Toxicology - January 10, 2017 Category: Toxicology Authors: Vispute SG, Bu P, Le Y, Cheng X Tags: Toxicology Source Type: research