Growth Differentiation Factor 15 Predicts All-Cause Morbidity and Mortality in Stable Coronary Heart Disease [Proteomics and Protein Markers]

CONCLUSIONS:
In stable CHD, GDF-15 was independently associated with CV, non-CV, and cancer mortality, as well as with MI and stroke. When also adjusting for other prognostic biomarkers, the associations to all fatal and nonfatal events were maintained except for MI. Information on GDF-15, therefore, might be helpful when assessing the risk of adverse outcomes in patients with stable CHD. ClinicalTrials.gov Identifier: NCT00799903

Source: Clinical Chemistry - December 29, 2016 Category: Chemistry Authors: Hagstrom, E., Held, C., Stewart, R. A. H., Aylward, P. E., Budaj, A., Cannon, C. P., Koenig, W., Krug-Gourley, S., Mohler, E. R., Steg, P. G., Tarka, E., Ostlund, O., White, H. D., Siegbahn, A., Wallentin, L., on behalf of the STABILITY Investigators Tags: Proteomics and Protein Markers Source Type: research