Neurologic Complications in Childhood Cancer

Though the treatment of pediatric cancers has come a long way, acute and chronic effects of cancer are still impacting the life of many children. These effects may be caused not only by the malignancy itself but also by the interventions employed for the purpose of treatment. This review focuses primarily on the indirect effects of pediatric cancers and their treatment on the central and peripheral nervous system. Chemotherapy, radiation, and stem cell transplantation cause an immune compromised state and place the patient at risk of infection, the leading cause of mortality in pediatric cancer.
Source: Seminars in Pediatric Neurology - Category: Neurology Authors: Source Type: research