Phase II Weekly Vinblastine for Chemotherapy-Naive Children With Progressive Low-Grade Glioma: A Canadian Pediatric Brain Tumor Consortium Study [Pediatric Oncology]

Conclusion
Vinblastine administered once per week is well tolerated in children with treatment naïve PLGG. Overall survival and PFS are comparable to current therapies, with a favorable toxicity profile and a maintained quality of life.

Source: Journal of Clinical Oncology - October 4, 2016 Category: Cancer & Oncology Authors: Lassaletta, Scheinemann, Zelcer, Hukin, Wilson, Jabado, Carret, Lafay-Cousin, Larouche, Hawkins, Pond, Poskitt, Keene, Johnston, Eisenstat, Krishnatry, Mistry, Arnoldo, Ramaswamy, Huang, Bartels, Tabori, Bouffet Tags: Brain Tumors, Chemotherapy, CNS Tumors Pediatric Oncology Source Type: research