Striatal and Extrastriatal Dopamine Transporter Levels Relate to Cognition in Lewy Body Diseases (P2.009)

CONCLUSIONS: Caudate and extrastriatal dopamine dysfunction contribute in opposing directions to cognitive impairment in DLB.Study Supported by: Michael J. Fox Foundation (SNG, JHG.), National Alzheimer’s Coordinating Center Collaborative Project 5 U01 AG016976-11 (SNG, KAJ, JHG), the National Institute of Neurological Disorders and Stroke (KAJ), the National Institute on Aging (KAJ,TH), the Alzheimer’s Disease Association (KAJ), the Caja Madrid Foundation scholarship for postgraduate studies (MM), the Harvard Center for Neurodegeneration and Repair Pilot grant (SNG). Randy L. Buckner contributed to this study: his NIH funding supported HCS imaging.Disclosure: Dr. Gomperts has nothing to disclose. Dr. Marquie Sayagues has nothing to disclose. Dr. Locascio has nothing to disclose. Dr. Rentz has received personal compensation for activities with Elan Pharmaceuticals as a consultant. Dr. Becker has nothing to disclose. Dr. Hedden has nothing to disclose. Dr. Johnson has received personal compensation for activities with General Electric Healthcare, Avid Radiopharmaceuticals Inc., Siemens, and Genzyme Corp. Dr. Johnson has received personal compensation in an editorial capacity for American Society of Neuroimaging. Dr. Johnson has received research support from Avid Radiopharmaceuticals Inc., Janssen, and Pfizer Inc. Dr. Growdon has nothing to disclose.,

Source: Neurology - April 9, 2014 Category: Neurology Authors: Gomperts, S., Marquie Sayagues, M., Locascio, J., Rentz, D., Becker, A., Hedden, T., Johnson, K., Growdon, J. Tags: Movement Disorders II Source Type: research