Antibodies to paraoxonase 1 are associated with oxidant status and endothelial activation in rheumatoid arthritis

Conclusions: anti-PON1 antibodies can be responsible of PON1 impairment in RA patients, with a potential impact on biomarkers of oxidative status and endothelial activation. A gene-environment interaction of rs662 variants is supported.

Source: Clinical Science - August 11, 2016 Category: Biomedical Science Authors: Rodriguez-Carrio, J., Alperi-Lopez, M., Lopez-Mejias, R., Lopez, P., Ballina-Garcia, F. J., Abal, F., Gonzalez-Gay, M. A., Suarez, A. Tags: PublishAheadOfPrint Source Type: research