Down's syndrome is a risk factor for severe lower respiratory tract infection due to respiratory syncytial virus

Abstract AimPrevious studies have suggested that Down's syndrome is an independent risk factor for severe respiratory infection due to respiratory syncytial virus (RSV). We compared the clinical characteristics of children with and without Down's syndrome hospitalised due to RSV. MethodsThis retrospective cohort study compared data from hospitalisations due to RSV lower respiratory tract infections (LRTI) in children under 14 year of age with (n=58) and without (n=58) Down's syndrome. ResultsThe Down's group had longer hospital stays than the controls of six versus four days (p
Source: Acta Paediatrica - Category: Pediatrics Authors: Tags: Regular Article Source Type: research

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This study characterized and compared the implementation of clinically integrated community health workers (CHWs) to a certified asthma educator (AE-C) for low-income children with asthma. In the AE-C arm (N = 115), 51.3% completed at least one in-clinic education session. In the CHW arm (N = 108), 722 home visits were completed. The median number of visits was 7 (range, 0-17). Scheduled in-clinic asthma education may not be the optimal intervention for this patient population. CHW visit completion rates suggest that the schedule, location, and content of CHW asthma services better met patients' needs. Seven to 10 visits s...
Source: The Journal of Ambulatory Care Management - Category: Emergency Medicine Tags: Original Articles Source Type: research
CONCLUSIONS: For RCS, HRQOL in PD+HD patients was better than that in HD and comparable with that in PD patients, whereas the PCS, MCS, and KDCS HRQOL scores of PD+HD patients were comparable with those of HD and PD patients. PMID: 32063200 [PubMed - as supplied by publisher]
Source: Peritoneal Dialysis International - Category: Urology & Nephrology Tags: Perit Dial Int Source Type: research
ConclusionsCardiac rehabilitation programs containing exercise may provide broader cardiovascular benefits compared to those without exercise.
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
Publication date: Available online 18 February 2020Source: Best Practice &Research Clinical AnaesthesiologyAuthor(s): Andrea De Gasperi, Gregorio Spagnolin, Martina Ornaghi, Laura Petrò, Gianni BiancofioreAbstractNew and extended indications, older age, higher cardiovascular risk, and the long-standing cirrhosis - associated complications mandate specific skills for an appropriate preoperative assessment of the LT candidate. The incidence of cardiac diseases (dysrhythmias, cardiomyopathies, coronary artery disease, valvular heart disease) are increasing among LT recipients: however, no consensus exists among cli...
Source: Best Practice and Research Clinical Anaesthesiology - Category: Anesthesiology Source Type: research
ConclusionsThese survey results suggest that the PLLR format was not known by a majority of prescribers and that the pregnancy letter category format is continuing to be used despite significant flaws in the old system. However, the survey did not address why prescribers were continuing to rely on the pregnancy letter category system. Whether this is due to the PLLR format itself or the lack of quality data to inform the safe use of medications in pregnancy cannot be determined from these survey results. FDA will use these survey results to refine the communication of pregnancy safety information in labeling and will expan...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
ConclusionsResults of real-time telemedically delivered asthma education to improve QOL, enhance symptom management ability, and reduce symptom burden were positive or non-significant. No study indicated negative effects due to telemedicine. Limited results indicate that patient education can, under certain circumstances, positively influence asthma burden. Further validation of intervention methods and tools as well as outcome measurement consistency is recommended.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Publication date: Available online 18 February 2020Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Ryobu Mori, Hisako Matsumoto, Shigeo Muro, Hiroko Morisaki, Ryozo Otsuki
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Conclusion: Self-management behaviors and HrQoL of CHD patients in Chinese communities were inadequate. There is a positive correlation between self-management behaviors and HrQoL among CHD patients in Chinese community settings. Therefore, it is critical to improve self-management behaviors and HrQoL of CHD patients in Chinese communities.Impact statement: Self-management behaviors were found to positively influence on HrQoL among CHD patients in Chinese community settings. It is necessary to develop the nursing intervention on self-management behaviors to enhance the HrQoL of CHD patients in Chinese communities. PMID...
Source: Contemporary Nurse - Category: Nursing Tags: Contemp Nurse Source Type: research
Source: The Doctors Lounge - Oncology - Category: Cancer & Oncology Tags: Cardiology, Gynecology, Oncology, News, Source Type: news
Abstract Germline genome editing has garnered dire predictions about its societal effects, but experience with other reproductive technologies should caution us about making extravagant claims. Amniocentesis was predicted to result in increased stigmatization of people born with Down syndrome, but in fact people with these conditions have been increasingly integrated into schools and workplaces. Artificial insemination by donor was predicted to result in women choosing to "optimize" their children, but in fact most women eschewed the offerings of the so-called "genius sperm bank," and when choo...
Source: Perspectives in Biology and Medicine - Category: Medical Ethics Authors: Tags: Perspect Biol Med Source Type: research
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