Low oxygen, high risk: How tumors adapt to become more aggressive

(The Wistar Institute) Wistar scientists have identified a novel mechanism that selectively operates in hypoxic tumors to enable tumor cells to thrive and continue to proliferate despite a low oxygen environment. Dario C. Altieri, M.D., Wistar's President and CEO and lead author of the study, and colleagues showed how the activation of this pathway leads to an unfavorable prognosis for patients with gliomas -- a type of brain tumor -- and how the pathway could be a valuable therapeutic target in cancer.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news