Can a Smell Test Predict Early Stages of Alzheimer ’s Disease?

Researchers report that an odor identification test may prove useful in predicting cognitive decline and detecting early-stage Alzheimer ’s disease. By Alzheimer's Reading Room I wrote about the smell test many times here in the Alzheimer's Reading Room. It interests me not only because it would be a good way to detect Alzheimer's; but also I think it relates to why it is often difficult to get dementia patients to eat more food. Thing about it? What usually happens when you smell food cooking? If it smells good - you get hungry. Those saliva glands get in action. How to encourage a dementia patients to eat Subscribe to the Alzheimer's Reading Room When I first read about this way back in 2004, I asked my mother if she could smell this and that. I often wondered what would have happened if I had read the article in 2000? Would I have given my mother the smell test? If so, and she couldn't smell things would I have taken action with her doctor? I'll never know. Alzheimer's caregiver? Learn more about a clinical research study that is currently enrolling new participants. or Quick link to the pre-qualify questionnaire One thing I do know. If a person starts having memory problems it would probably be a good idea to bring this up with a good doctor well versed in dementia research and dementia care. You might consider passing this information along if you live in a community of seniors. How to Get Answers To Your Questions About Alzheimer's and...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: alzheimer's and dementia alzheimers care dementia care family caregiving help alzheimer's memory care odor identification smell test Source Type: blogs

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Alzheimer’s disease (AD) is a neurodegenerative disease and the main cause of dementia. Its major symptom is memory loss, which is a result of neuronal cell death, which is accompanied by neuroinflammation. Some studies indicate the overactivation of the phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt)/mechanistic target of rapamycin (mTOR) pathway in this disease, being, thus, a potential target for pharmacological treatment. Here, we used a transgenic mouse model of AD that expresses a mutant amyloid-β precursor protein (T41 mice) to investigate the effects of dactolisib (alternative name: NVP-BEZ23...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
When we think of dementia, we think of memory loss, but that's vastly oversimplifying it. Most people have heard of Alzheimer's, but there are other types of dementia too, says DR ELLIE..
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Publication date: Available online 31 October 2019Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Ju Gao, Luwen Wang, Chao Gao, Hiroyuki Arakawa, George Perry, Xinglong WangAbstractAlzheimer's disease (AD) is the leading cause of dementia in the elderly, characterized clinically by progressive decline in cognitive function and neuropathologically by the presence of senile plaques and neuronal loss in the brain. While current drugs for AD are always employed as symptomatic therapies with variable benefits, there is no treatment to delay its progression or halt neurodegeneration. TAR DNA-bi...
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - Category: Molecular Biology Source Type: research
A UCLA-led study has found that MRI scans can help doctors distinguish whether a person ’s memory loss is being caused by Alzheimer’s disease or by traumatic brain injury.The study, which also involved researchers at Washington University in St. Louis, is important because it could help prevent doctors from misdiagnosing Alzheimer ’s disease — a diagnosis that can be devastating for patients and their families, and can prevent them from receiving appropriate treatment. (A 2016 study by researchers affiliated with the University of Toronto found that up to 21 percent of older adults with dementia may...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Authors: Rao YL, Ganaraja B, Joy T, Pai MM, Ullal SD, Murlimanju BV Abstract Alzheimer's disease (AD) is a neurodegenerative disorder, which is commonly seen in older individuals. This is characterized by cognitive dysfunction, which leads to dementia. Pharmacological treatments for AD are mainly targeted on its symptoms like memory loss and cognitive impairment. The pathophysiology involved in AD is intra-neuronal accumulation of hyper-phosphorylated tau protein as neurofibrillary tangle and extra cellular beta amyloid plaque deposition, which is due to oxidative stress. Here we review the neuro-protective effects...
Source: Frontiers in Bioscience - Elite - Category: Biomedical Science Tags: Front Biosci (Elite Ed) Source Type: research
To delay or prevent the onset of memory loss, talk to your doctor. It can really be that simple. Among the diseases that Americans fear most, Alzheimer ’s and dementia consistently rank at the top of the list. What people don’t always realize is that many causes of memory loss are treatable and preventable, and the […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more.
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions Neurology Primary Care Source Type: blogs
After spending 30 minutes hunting for your car in a parking lot, or getting lost on a familiar route, have you ever considered asking your doctor for a blood test or brain scan to find out if you have Alzheimer’s disease? A number of factors contribute to Alzheimer’s disease. By definition, this form of dementia involves the buildup of a protein in brain called beta-amyloid. Beta-amyloid forms plaques that disrupt communication between brain cells, and ultimately destroys them. For this reason, tests for Alzheimer’s disease focus on beta-amyloid. Blood tests for Alzheimer’s disease are being develop...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Alzheimer's Disease Healthy Aging Memory Tests and procedures Source Type: blogs
A clinical trial has found that an innovative electromagnetic therapy device significantly reduced memory loss in seven out of the eight participants.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Alzheimer's / Dementia Source Type: news
“Get out! Get out!” My wife, Joan, having just woken up, was screaming, and hitting out wildly at the stranger in her bed. She was in a panic, her body shaking with fright. “Get away from here. Get out!” The man she perceived as a stranger was me, her husband of more than forty years. Joan was eight years into the destructive course of atypical early-onset Alzheimer’s disease, a horrific disorder that ravaged her, leaving her blind and with serious dementia. At that moment, she was experiencing something called Capgras Syndrome, in which patients become deluded that those close to them and the...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Books health ideas Source Type: news
Alzheimer's disease (AD) is the most common cause of dementia but the changes in brain cell function underlying memory loss remains poorly understood. Researchers at the University of Bristol have identified that calcium channel blockers may be effective in treating memory loss.
Source: University of Bristol news - Category: Universities & Medical Training Tags: Health, International, Research; Faculty of Life Sciences, Faculty of Life Sciences, School of Physiology, Pharmacology and Neuroscience; Press Release Source Type: news
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