Green Chemistry Is The Path To Chemical Safety

Co-authored by Glynis Lough On June 22nd, the Frank R. Lautenberg Chemical Safety for the 21st Century Act was signed into law, bringing the first legislative reform to chemical management regulation in 40 years! From car seats to zippers, nearly every product in and out of the home has the potential to change because of this bill - meaning your favorite toy or cooking pan could be reformulated because chemicals toxic to human health are used in the production.  And the bill also includes special protections for women's and children's health. Sound great?  Sort of.  The reality of the bill is that it's a mixed bag - only twenty chemicals of the thousands and thousands that are actually used in consumer goods are required to be tested per year, and there's a 64,000 backlog - but with increased authority, the Environmental Protection Agency (EPA) can prevent new problems from entering the market. That means that real effort is needed to make this bill more than just public relations. To be sure, there are some good things in this bill, such as setting new safety standards for chemicals with ties to cancer, mental health, and infertility and allowing the Environmental Protection Agency (EPA) to obtain more information about a chemical before approving its use. We need more action to pollute less. What this really means is that we need to find other ways to protect people and the environment from the chemicals that we routinely use, like dry cleaning ...
Source: Science - The Huffington Post - Category: Science Source Type: news

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The objective of this compound is to decrease the rate of rectal toxicity related to radiation therapy, by creating a gap between the prostate and rectum. Secondary benefits include decreased urinary complications and improved sexual quality of life. The hydrogel spacer maintains space for approximately 3 months, and is absorbed in about 6 months.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 43: Follow Your Gut Source Type: research
To evaluate the efficacy and clinical impact of 3 Tesla in-bore trans-rectal magnetic resonance-guided biopsy (3T MRGB) for prostate cancer (PCa) detection based on PIRADSv2 in patients with either suspected prostate cancer or under active surveillance.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 43: Follow Your Gut Source Type: research
We describe our experience using MRI fused CBCT guidance for prostate biopsy. There are no published reports on the use of CBCT guidance in prostate biopsies. We hypothesize this technique will have an adequate safety profile while accurately detecting prostate cancer.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 39: Needle in a Haystack (Biopsies) Source Type: research
Image-guided thermal ablation has become the standard of care for treating early stage liver cancer. However, a significant limitation to a successful ablation procedure is the heat-sink effect, which may lead to suboptimal thermal dose delivery. Currently, there is no reliable method for quantifying the heat-sink effect due to limited information on blood vessel flow and its associated anatomy relative to the ablation zone. The purpose of this study was to use 4D-flow MRI to map out liver flow patterns and correlate flow rates with ablation zone volumes.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 38: All Kinds of Thermal Source Type: research
Biphenotypic hepatocellular-cholangiocarcinoma (HCC-CC) is a rare type of primary liver cancer that carries a poor prognosis. Since most patients present at a stage too advanced for surgical resection, loco-regional liver directed therapy is often performed for palliative or downstaging purposes. The purpose of this study is to evaluate patient outcomes after Yttrium-90 radioembolization (Y90) in patients with HCC-CC.
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 34: Y-90 Y Not (Radioembolization II) Source Type: research
Immunotherapy is a paradigm-shifting advance in cancer care, but the overall response rates remain low. There has been a renaissance in the concept of promoting the immune-responsiveness of the tumor immune microenvironment via intratumoral (IT) delivery of immunostimulatory agents. However, the optimal method for IT delivery of such medications that maximizes IT dispersion while minimizing perilesional leakage and systemic distribution is unknown. The purpose of this study was to characterize IT drug distribution and its influence on drug efficacy using conventional end-hole needles (EHNs) versus multi-sidehole needles (MSHN).
Source: Journal of Vascular and Interventional Radiology : JVIR - Category: Radiology Authors: Tags: Scientific Session 33: IO IO, It ’s Off to Work We Go Source Type: research
Authors: Mathur P, Jha S, Ramteke S, Jain NK Abstract Silver nanoparticles are particles in the size ranging between 1 and 100 nm. The two major methods used for synthesis of silver nanoparticle are the physical and chemical methods with the disadvantage that they are expensive and can also have toxicity. Biological method is being used as an expedient alternative, as this approach is environment-friendly and less toxic and it includes plant extracts, microorganism, fungi, etc. The major applications of silver nanoparticles in the medical field include diagnostic applications and therapeutic applications, ap...
Source: Artificial Cells, Nanomedicine and Biotechnology - Category: Biotechnology Tags: Artif Cells Nanomed Biotechnol Source Type: research
Conclusion: To address the many challenges posed by EDCs, we argue that Africans should take the lead in prioritization and evaluation of environmental hazards, including EDCs. We recommend the institution of education and training programs for chemical users, adoption of the precautionary principle, establishment of biomonitoring programs, and funding of community-based epidemiology and wildlife research programs led and funded by African institutes and private companies. https://doi.org/10.1289/EHP1774 Received: 16 February 2017 Revised: 22 May 2017 Accepted: 24 May 2017 Published: 22 August 2017 Address correspond...
Source: EHP Research - Category: Environmental Health Authors: Tags: Commentary Source Type: research
Endometriosis currently affects ~5.5 million reproductive-aged women in the U.S. with symptoms such as painful periods (dysmenorrhea), chronic pelvic pain, pain with intercourse (dyspareunia), and infertility. It is defined as the presence of endometrial tissue outside the uterine cavity and is found predominately attached to sites within the peritoneal cavity. Diagnosis for endometriosis is solely made through surgery as no consistent biomarkers for disease diagnosis exist. There is no cure for endometriosis and treatments only target symptoms and not the underlying mechanism(s) of disease. The nature of individual predis...
Source: Reproduction - Category: Reproduction Medicine Authors: Tags: Reviews Source Type: research
Mozambique doesn't have any living rhinos left, but the country is still a hub for the illicit, and highly lucrative, trade in endangered animal parts. In an increasingly common show of force against poachers, wildlife officials destroyed more than 425 pounds of rhino horn and two tons of elephant ivory on Monday. The cache was seized in Maputo, Mozambique's capital, earlier this year in what The Guardian calls the biggest haul of rhino horn ever. The goods represent more than 200 animals that were killed for their horns and tusks, according to Agence France-Presse. Based on conservative estimates, the total value of th...
Source: Science - The Huffington Post - Category: Science Source Type: news
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