Hydrocortisone as an Intervention for Dexamethasone-Induced Adverse Effects in Pediatric Patients With Acute Lymphoblastic Leukemia: Results of a Double-Blind, Randomized Controlled Trial [Pediatric Oncology]

Conclusion
Our results suggest that adding a physiologic dose of hydrocortisone to dexamethasone treatment can reduce the occurrence of serious neuropsychological adverse effects and sleep-related difficulties in pediatric patients with ALL.

Source: Journal of Clinical Oncology - June 21, 2016 Category: Cancer & Oncology Authors: Warris, van den Heuvel-Eibrink, Aarsen, Pluijm, Bierings, van den Bos, Zwaan, Thygesen, Tissing, Veening, Pieters, van den Akker Tags: Developmental Therapeutics & Pharmacology, Acute Lymphoblastic Leukemia, Supportive Care Pediatric Oncology Source Type: research