Pharmacotherapy Utilisation in Alcohol Dependence
Conclusion
Pharmacotherapy in this cohort has the potential to increase success of clinical pathways but may be under-utilised in practice. This patient cohort is often difficult to engage and resistant to change. This may be compounded however by our lack of understanding of what therapies will be effective for each individual. This lack of stratification early in the treatment pathway may lead to a negative treatment outcome that disengages the patient. Looking ahead, translational research is required to identify novel therapeutic targets that can be developed into targeted therapies for alcohol dependence or broader alcohol use disorders. A strong scientific grounding is required to ensure any stratification markers or therapies that are developed are effective and provide confidence to the prescriber and patient.
Further Information
Dr Andrew Thompson
Wolfson Centre for Personalised Medicine, Molecular & Clinical Pharmacology, University of Liverpool
References
Ashley, M. J., Olin, J. S., Le Riche, W. H., Kornaczewski, A., Schmidt, W. & Rankin, J. G. (1977). Morbidity in alcoholics: evidence for accelerated development of physical disease in women. Archives of Internal Medicine, 137, 883-887.
Herrett, E., Gallagher, A. M., Bhaskaran, K., Forbes, H., Mathur, R., Van Staa, T. & Smeeth, L. (2015). Data Resource Profile: Clinical Practice Research Datalink (CPRD). Internat...
Source: Alcohol Research UK - Category: Addiction Authors: admin Tags: Alcohol Insights Source Type: news
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