Clinical implications for Translocator Protein (TSPO) imaging using [123I]CLINDE SPECT: A feasible approach

Conclusions The preliminary results imply that [123I]CLINDE-SPECT is a feasible approach for TSPO imaging in neurological disorders associated with microglial activation and/or increased TSPO expression. The development of methods that do not need arterial blood sampling for quantification of TSPO will be important to ease implementation in a daily clinical setting. Further clinical studies are needed to determine the precise role of TSPO imaging in predicting clinical outcome and treatment response.
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: Neurosciences/Neurology. Miscellaneous Source Type: research