How Getting a Puppy Helped My Terminally Ill Teen

The puppy was 10 weeks old and a little over a pound the day we brought him home. He was a fancy mutt, a combination miniature poodle and Yorkshire terrier (yorkie-poo) that will likely grow no larger than five or six pounds. My 14-year-old daughter was in Manhattan getting radiation for tumors in her lungs the day I picked him up - he was a surprise that would be waiting for her that night. I'd originally told her we would get a dog when radiation treatments were over -- something for her to look forward to after three weeks of daily trips to the hospital (a six-hour round trip from our home in the Hudson Valley). I kept my younger daughter home from school the day we got him, mostly because I was terrified of being alone with a dog, even one so small. I've been a cat person all my life. "I don't know about this," I'd said as we drove away from the kennel. "This is the best day of my life," my daughter had responded. The puppy was curled up in her lap, looking a bit uncertain himself. We named him Roo (after the Winnie the Poo character) because he hopped around so much. He was my responsibility for the first month. My husband needed to focus on getting enough rest for the daily drives, and my older daughter, exhausted from the commute and double dose of radiation, barely had enough energy to greet him each evening before going upstairs to rest. "He smells," she said the first day. So I gave him a bath. Roo slept in a crate each night wi...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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J Oral Sci. 2018 Aug 30. doi: 10.2334/josnusd.17-0381. [Epub ahead of print]AbstractUsing a controlled pre/post study design, we investigated the effects of professional mechanical cleaning of the oral cavity with benzethonium chloride, interdental brushes, and hydrogen peroxide on the number of oral bacteria and postoperative complications among esophageal cancer patients in an intensive care unit. Before surgery, 44 patients with esophageal cancer were recruited at Okayama Hospital from January through August 2015. The control group (n = 23) received routine oral hygiene care in the intensive care unit. The intervention ...
Source: Dental Technology Blog - Category: Dentistry Source Type: news
We report a patient with highly advanced gastric carcinoma who was treated successfully with chemoradiotherapy (CRT) comprising S-1 and cisplatin. The patient was a 71-year-old male who was diagnosed with advanced gastric carcinoma by esophagogastroduodenoscopy (EGD) by medical examination. EGD demonstrated type 3 advanced gastric carcinoma in the posterior wall of the upper gastric body. An abdominal computed tomography (CT) scan showed that the gastric wall was thickened due to gastric primary tumor, and large lymph nodes (LNs) including the lesser curvature LN, anterosuperior LN along the common hepatic artery and some ...
Source: Case Reports in Gastroenterology - Category: Gastroenterology Source Type: research
AbstractThe Clinical Oncology of  American Society report in 2016 predicted deaths are increased upto 9570 due to oral cancer. This cancer occurs due to abnormal tissue growth in the oral cavity. This cancer has limited symptoms, so, it has been difficult to recognize in the early stages. To reduce the death rate of this oral cavi ty cancer, an automatic system has been developed by applying the optimization techniques in both image processing and machine learning techniques. Even though these methods are successfully recognizing the cancer, the detection accuracy is still one of the major issues because of complex or...
Source: Journal of Medical Systems - Category: Information Technology Source Type: research
Publication date: Available online 18 September 2018Source: Journal of Pharmaceutical and Biomedical AnalysisAuthor(s): Riyazuddin Mohammed, R. Valicherla Guru, Husain Athar, Kamil Hussain Mohd, Shukla Minakshi, Katekar Roshan, P. Gupta Anand, Singh Pragati, Banerjee Dibyendu, Hajela Kanchan, R. Gayen JiaurAbstractS012-1332 is the first DNA ligase I inhibitor that demonstrated in vivo anti-breast cancer activity. The present study aimed to assess the in vivo pharmacokinetics of S012-1332 in rats and interpret them with in vitro findings. A sensitive and selective liquid chromatography-tandem mass spectrometry bioanalytical...
Source: Journal of Pharmaceutical and Biomedical Analysis - Category: Drugs & Pharmacology Source Type: research
This study sought to develop a simple and sensitive competitive enzyme-linked immunosorbent assay (ELISA) to quantify afatinib in plasma for routine pharmacokinetic applications. An anti-afatinib antibody was obtained using (S)-N-4-(3-chloro-4-fluorophenyl)-7-(tetrahydrofuran-3-yloxy)-quinazoline-4,6-diamine (CTQD), which has the same substructure as afatinib, as a hapten. Enzyme labeling of afatinib with horseradish peroxidase was similarly performed using CTQD. A simple competitive ELISA for afatinib was developed based on the principle of direct competition between afatinib and the enzyme marker for the anti-afatinib an...
Source: Journal of Pharmaceutical Analysis - Category: Drugs & Pharmacology Source Type: research
Conclusion: LCH not only induces apoptosis in OSCC cells through the JAK/STAT3 signaling pathway but also inhibits cell growth. It is proposed that LCH has a promising use for the chemotherapeutic agent of oral cancer.Graphical abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research
Clinical-stage drug discovery company Galera Therapeutics has raised $150 million in a Series C financing and royalty purchase agreement. According to a release, it is the largest ever Series C raise by a St. Louis bioscience company. Led by Clarus, proceeds from the raise will be used for the clinical development of the drug GC4419, which has shown to reduce the incidence and duration of severe oral mucositis, a side effect of radiation treatment in head and neck cancer patients that causes painful…
Source: bizjournals.com Health Care News Headlines - Category: Health Management Authors: Source Type: news
Authors: Franzmann EJ, Donovan MJ Abstract INTRODUCTION: Head and neck cancer remains a challenging disease that is increasing in incidence with the majority of patients diagnosed at an advanced stage where five-year survival is approximately 50%. Current approaches including oral-brush biopsies, fluorescence-based technologies and salivary molecular profiling have demonstrated some success; however, cost, ease of use and accuracy remain limiting factors. Areas Covered: This is a profile of a novel, easy to use oral rinse point-of-care (POC) test to aid in the diagnosis of oral and oropharyngeal cancer. Background ...
Source: Expert Review of Molecular Diagnostics - Category: Laboratory Medicine Tags: Expert Rev Mol Diagn Source Type: research
(NRG Oncology) An analysis of the NRG Oncology clinical trial NRG-GY003 suggests that adding ipilimumab, a monoclonal antibody that targets the protein receptor CTLA-4, to a regimen with the checkpoint inhibitor nivolumab could improve the proportion with tumor response and progression-free survival hazard rates for women with recurrent epithelial ovarian cancer. These results were presented as a late-breaking abstract oral presentation at the 17th Biennial Meeting of the International Gynecological Cancer Society (IGCS) in Kyoto, Japan.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
Authors: Qui L, Tan H, Yin H, Zhou J, Cheng D, Shi H Abstract BACKGROUND: The aim was to compare the detect ability of 3 sequential 131I whole-body scans (tri-WBS) on the second, third, and fourth day after 131I therapy for metastatic thyroid cancer. METHODS: Differentiated thyroid cancer patients who received oral high-dose 131I therapy underwent routinely tri-WBS on the second, third, and fourth day after total or near-total thyroidectomy in our hospital. We enrolled 137 patients with 261 tri-WBSs in this study between January 2015 and November 2017. The inclusion criteria was that at least one metastasis was...
Source: Quarterly Journal of Nuclear Medicine and Molecular Imaging - Category: Nuclear Medicine Tags: Q J Nucl Med Mol Imaging Source Type: research
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