How Getting a Puppy Helped My Terminally Ill Teen

The puppy was 10 weeks old and a little over a pound the day we brought him home. He was a fancy mutt, a combination miniature poodle and Yorkshire terrier (yorkie-poo) that will likely grow no larger than five or six pounds. My 14-year-old daughter was in Manhattan getting radiation for tumors in her lungs the day I picked him up - he was a surprise that would be waiting for her that night. I'd originally told her we would get a dog when radiation treatments were over -- something for her to look forward to after three weeks of daily trips to the hospital (a six-hour round trip from our home in the Hudson Valley). I kept my younger daughter home from school the day we got him, mostly because I was terrified of being alone with a dog, even one so small. I've been a cat person all my life. "I don't know about this," I'd said as we drove away from the kennel. "This is the best day of my life," my daughter had responded. The puppy was curled up in her lap, looking a bit uncertain himself. We named him Roo (after the Winnie the Poo character) because he hopped around so much. He was my responsibility for the first month. My husband needed to focus on getting enough rest for the daily drives, and my older daughter, exhausted from the commute and double dose of radiation, barely had enough energy to greet him each evening before going upstairs to rest. "He smells," she said the first day. So I gave him a bath. Roo slept in a crate each night wi...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news

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This study was based on a randomized controlled trial (NCT01998230). Patients with esophageal cancer who received McKeown MIE were randomly allocated into a group that started oral feeding on postoperative day (POD) 1 (EOF group) or a second group that received nil by mouth until 7 days after operation (late oral feeding [LOF] group). We chose 86 patients, 46 patients in the EOF group and 40 patients in the LOF group, in which to analyze inflammatory cytokine levels (interleukin [IL]-6, IL-8, tumor necrosis factor-a [TNF-α], and monocyte chemotactic protein-1 [MCP-1]).ResultsThe EOF and LOF groups exhibited similar p...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Authors: Laparra J, Fotschki B, Haros C Abstract Imbalances in innate immunity and the activity of innate immune cells are implicated in the development of hepatocellular carcinoma (HCC). Plant seeds are good sources of protease inhibitors, which can have a significant influence on human health disorders, especially in the field of cancer prevention. To elucidate the impact and preventive effects of immunonutritional serine-type protease inhibitors (STPIs) on HCC, it was used an established model of chemically induced liver injury. Injured livers induced Akt as well as hepatic infiltration of NKG2D + and CD74 + cel...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
Publication date: Available online 19 February 2019Source: Journal of Bone OncologyAuthor(s): C. Wilson, C. Martin, M.C. WinterAbstractBackgroundAdjuvant bisphosphonates (BPs) are recommended as part of routine early breast cancer treatment for many postmenopausal (PM) women within the past year. There is a paucity of ‘real world’ data on compliance and patient satisfaction with oral BPs in this population. The aim of our study was to investigate patient reported compliance and toxicity of these drugs in a retrospective cohort study.Patients and methods413 patient were identified as receiving adjuvant oral BPs ...
Source: Journal of Bone Oncology - Category: Cancer & Oncology Source Type: research
Gastric acid suppressants may reduce absorption of oral cancer drugs, as shown in a study with pazopanib for sarcoma in which the interaction led to worse outcomes. Can this be practice changing?Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
Introduction: Breast cancer (BC) epidemic is characterized by around half a million deaths and 1.7 million new cases registered annually worldwide. An epidemic scale of BC prevalence is actually recognized with increasing trends both in the post- and premenopausal BC prevalence and metastatic disease is major cause of death in this patient cohort. Particularly alarming is that the sporadic BC (90% of all patients) creates currently unpredictable subpopulations in terms of disease predisposition, development and progression.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Oral Poster at Breakfast 9 – Breast Source Type: research
Introduction: Breast cancer is the most common cancer it represents the second leading cause of death in the world. A molecular classification of this cancer has been recently established. The molecular classification of breast cancer based on gene expression and then on the protein profile allowed to distinguish five molecular groups: luminal A, luminal B, Her2/neu, basal-like and not classified.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Oral Poster at Breakfast 9 – Breast Source Type: research
Introduction: Netrins are a family of laminin-related extracellular matrix proteins which includes in humans the secreted netrin-1 and netrin-4. Both family members are not only involved in normal tissue development, but also in different types of malignancies. In primary breast cancer a direct correlation exists between the expression of netrin-1, the state of the disease and the generation of distant metastases. Netrin-4 expression in invasive breast tumors is a strong prognostic marker for overall survival.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Oral Poster at Breakfast 9 – Breast Source Type: research
Introduction: Circulating microRNA (miRNA) are a promising biomarker in metastatic breast cancer (MBC). Differing expression profiles for miRNA in primary tumor tissue and circulating miRNA is described.
Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology - Category: OBGYN Authors: Tags: Oral Poster at Breakfast 9 – Breast Source Type: research
Targeting the c-Met signaling pathway has become a therapeutic strategy in multiple types of cancer. We unveiled a novel c-Met regulating mechanism that could be applied as a modality for oral squamous cell ca...
Source: Journal of Experimental and Clinical Cancer Research - Category: Cancer & Oncology Authors: Tags: Research Source Type: research
Condition:   Head and Neck Cancer Interventions:   Other: Standard of Care Oral Hygiene;   Procedure: Oral mucosal deterging and dental prophylaxis Sponsor:   Abramson Cancer Center of the University of Pennsylvania Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
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