Germ stem cells are active in postnatal mouse ovary under physiological conditions
This study was conducted in mice. Whether or not the results are applicable to human remain unclear. The future work should aim at identifying the specific ovarian germ stem cell marker and evaluating the significance of these stem cells to normal ovarian function.
WIDER IMPLICATIONS OF THE FINDINGS
Clarifying the existence of active germ stem cells and their functional significance in postnatal mammalian ovaries could provide new insights in understanding the mechanism of ovarian aging and failure.
LARGE SCALE DATA
Not applicable.
STUDY FUNDING/COMPETING INTEREST(S)
This work was supported by the National Key Basic Research Program of China (grant number 2012CBA01300) and the National Natural Science Foundation of China to P.Z. (31571484). No competing interests are reported.
Source: Molecular Human Reproduction - Category: Molecular Biology Authors: Guo, K., Li, C.-h., Wang, X.-y., He, D.-j., Zheng, P. Tags: Articles Source Type: research
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