miR-21 promotes fibrosis in an acute cardiac allograft transplantation model

Conclusion
Thus, inhibition of miR-21 is a novel strategy to target fibrosis development in cardiac allografts.

Source: Cardiovascular Research - April 18, 2016 Category: Cardiology Authors: Gupta, S. K., Itagaki, R., Zheng, X., Batkai, S., Thum, S., Ahmad, F., Van Aelst, L. N., Sharma, A., Piccoli, M.-T., Weinberger, F., Fiedler, J., Heuser, M., Heymans, S., Falk, C. S., Förster, R., Schrepfer, S., Thum, T. Tags: Cardiac biology and remodelling Source Type: research